張冬冬

個人簡介
中國海洋大學 生物科學學士,中國海洋大學 水生生物學碩士,美國奧本大學(Auburn University)水産漁業科學博士。2019年10月入職365英国上市官网在线,副教授,海南省D類高層次人才。主持國家自然科學基金、海南省自然科學基金等多項科研項目,在 Fish and Shellfish Immunology和Aquaculture等雜志發表SCI論文20餘篇,參編研究生《水産動物免疫學》教材一部。
研究方向和内容
研究方向為水産動物免疫與病害學,主要研究内容包括:(1)利用免疫學與分子生物學尤其是前沿組學的理論與技術,研究魚類粘膜免疫系統的細胞分型、機體與病原相互作用的分子機制;(2)水産魚類關鍵疾病(例如羅非魚柱形病、石斑魚腸孢子蟲病等)的快速準确檢測技術和高效防控策略的開發與應用;(3)水産魚類關鍵疾病的抗病基因和分子标記的篩選,以及抗病育種研究。相關研究豐富了水産動物免疫學的研究内容,推進了水産魚類健康養殖與安全有效疾病防控策略的開發。
主持科研項目
國家自然科學基金青年項目,羅非魚鼠李糖凝集素(OnRBL)介導柱狀黃杆菌粘附侵染的分子機制,2024-01至2026-12,主持。
羅非魚重要細菌性病原人工感染模型的建立及抗病品系選育項目,橫向課題,2023-05至2025-05,主持。
海南省自然科學基金項目, 羅非魚鰓粘膜組織細胞分型, 2020-12 至 2023-12,主持。
海南省重大科技計劃項目-子課題 高體鰤人工繁育與安全生産關鍵技術研究與應用示範-疾病防控任務,2021-12 至 2024-12,主持。
廣東省水産經濟動物病原生物學及流行病學重點實驗室開放課題,羅非魚柱狀黃杆菌病原侵染機制研究,2021-09 至 2023-09, 主持。
365英国上市官网在线高層次人才校級科研啟動項目,海南重要養殖魚類分子免疫機制研究,2020-01到2024-12,主持。
代表論文
Dongdong Zhang, Gengfu Zhou, Wilawan Thongda, Chao Li, Zhi Ye, Honggang Zhao, Benjamin H. Beck, Haitham Mohammed, Eric Peatman. Early divergent responses to virulent and attenuated vaccine isolates of Flavobacterium columnare in channel catfish, Ictalurus punctatus. 2024, 144: 109248.
Peibo Wang#1, Yongcan Zhou#1, Bei Wang, Ahmed Elaswad, Shifeng Wang, Weiliang Guo, Dongdong Zhang*. Single-cell suspension preparation from Nile tilapia intestine for single-cell sequencing, Journal of Visualized Experiments, 2023, (192): 1-12
Dongdong Zhang, Haitham Mohammed, Zhi Ye, Melanie A. Rhodes, Wilawan Thongda, Honggang Zhao, Lauren N Jescovitch, S Adam Fuller, D Allen Davis, Eric Peatman. Transcriptomic profiles of Florida pompano (Trachinotus carolinus) gill following infection by the ectoparasite Amyloodinium ocellatum. Fish and Shellfish Immunology, 2022,125:171-179.
Dongdong Zhang, Wilawan Thongda, Chao Li, Honggang Zhao, Benjamin H. Beck, Haitham Mohammed, Covadonga R. Arias, Eric Peatman*. More than just antibodies: Protective mechanisms of a mucosal vaccine against fish pathogen Flavobacterium columnare. Fish and Shellfish Immunology, 2017, 71: 160-170.
Dongdong Zhang, Benjamin H. Beck, Honggang Zhao, Wilawan Thongda, Zhi Ye, Qifan Zeng, Craig A. Shoemaker, S. Adam Fuller, Eric Peatman. L-Rhamnose-binding lectins (RBLs) in Nile tilapia, Oreochromis niloticus: Characterization and expression profiling in mucosal tissues. Fish and Shellfish Immunology, 2018, 72: 426-435.
Dongdong Zhang, Benjamin H. Beck, Miles Lange, Honggang Zhao, Wilawan Thongda, Zhi Ye, Chao Li, Eric Peatman*. Impact of oral and waterborne administration of rhamnolipids on the susceptibility of channel catfish (Ictalurus punctatus) to Flavobacterium columnare infection, Fish and Shellfish Immunology, 2017, 60: 44-49.
Yangen Zhou#1, Dongdong Zhang#1, Eric Peatman, Melanie A. Rhodes, Jun Liu, D. Allen Davis*, Effects of various levelsof dietary copper supplementation with copper sulfate and copper hydroxychloride on Pacific white shrimp Litopenaeus vannamei performance and microbial communities. Aquaculture, 2017, 476: 94-105.
Chengbin Gao#1, Baofeng Su#1, Dongdong Zhang#1, Ning Yang, Lin Song, Qiang Fu, SHUN- Zhou, Fenghau Tan, Chao Li. L-rhamnose-binding lectins (RBLs) in turbot (Scophthalmus maximus L.): Characterization and expression profiling in mucosal tissues. Fish and Shellfish Immunology, 2018, 80: 264-273.
Yun Sun#1, Dongdong Zhang#1, Jianzhi Shi#1, Guisen Chen, Ying Wu, Yang Shen, Zhenjie Cao, Linlin Zhang*, Yongcan Zhou*, A chromosome-level genome assembly and annotation of the humpback grouper Cromileptes altivelas. bioRxiv 2020.06.22.164277; doi: https://doi.org/10.1101/2020.06.22.164277.
Zhengqiang Chen, Dongdong Zhang, Jing Xing*, Wenbin Zhan, Effects of temperature on haemocyte and granulocyte counts and expressions of immunity-related genes in haemocytes of scallop Chlamys farreri after Vibrio anguillarum Infection. J. Ocean Univ. China. (Oceanic and Coastal Sea Rese). 2019, 5: 1-11.
招生專業
水生生物學博士、水産養殖學術碩士、漁業發展專業碩士
聯系方式
電子郵箱:zdd88312@hainanu.edu.cn
辦公室:南海海洋資源利用國家重點實驗室 517