葉鼎

個人簡介：

1983年生，博士、教授，魚類生物技術與種質創新團隊Co-PI，中國實驗動物學會水生實驗動物專業委員會秘書長。在Science China Life Sciences, Development，PLOS Genetics，Endocrinology，Frontiers in Endocrinology等學術刊物上發表論文40餘篇, 多篇高引論文和亮點推薦論文，授權國家發明專利多項。

學術成果：

圍繞魚類生殖細胞發育和生物技術研究方向，闡明了斑馬魚性腺發育和配子發生進程；解析了雄激素在魚類性腺發育、配子發生、生殖行為中的調控作用；揭示了控制生殖幹細胞向卵母細胞分化的關鍵因子及其作用機制；實現多種魚類生精細胞的精細分型和鑒定；建成了普适性高的魚類借腹生殖技術體系；實現用小型實驗魚快速生産草魚、團頭鲂等大型經濟魚的成熟精子。

研究方向：

1. 海水經濟魚類基因編輯和借腹生殖前沿育種技術研究；

2. 海洋活性物質評價實驗魚模型的定制與規模化生産。

近五年代表性論文：

1. Zhiqin Ren, Ding Ye*, Naike Su, Chaofan Wang, Lijia He, Houpeng Wang, Mudan He, Yonghua Sun. 2024. foxl2l is a germ cell-intrinsic gatekeeper of oogenesis in zebrafish. Zoological Research. DOI: 10.24272/j.issn.2095-8137.2024.046.

2. Ding Ye†, Tao Liu†, Yongming Li, Yaqing Wang, Wei Hu, Zuoyan Zhu, Yonghua Sun. Identification of fish spermatogenic cells through high-throughput immunofluorescence against testis with an antibody set. Front Endocrinol (Lausanne). 2023 Apr 3;14:1044318. doi: 10.3389/fendo.2023.1044318.

3. Qifeng Zhang†, Ding Ye†, Houpeng Wang, Yaqing Wang, Wei Hu, Yonghua Sun*, Zebrafish cyp11c1 Knockout Reveals the Roles of 11-ketotestosterone and Cortisol in Sexual Development and Reproduction, Endocrinology, 2021, 161(6): bqaa048.(2019-2020年度及2020-2021年度Endocrinology雜志高被引論文)

4. Ding Ye†, Xiaosi Wang†, Changyong Wei†, Mudan He, Houpeng Wang, Yaqing Wang, Zuoyan Zhu, Yonghua Sun. Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b. PLoS Genet. 2019, 15(9): e1008306.

5. Ding Ye†, Lin Zhu†, Qinfeng Zhang, Feng Xiong, Houpeng Wang, Xiaosi Wang, Mudan He, Zuoyan Zhu, Yonghua Sun*. Abundance of Early Embryonic Primordial Germ Cells Promotes Zebrafish Female Differentiation as Revealed by Lifetime Labeling of Germline. Mar Biotechnol (NY). 2019, 21(2): 217-228.(Springer Nature 2019年度亮點論文)

6. Ding Ye*, Yi-Xuan Tu, Houpeng Wang, Mudan He, Yaqing Wang, Zhengfang Chen, Zhen-Xia Chen, Yonghua Sun*, A landscape of differentiated biological processes involved in the initiation of sex differentiation in zebrafish, Water Biology and Security, 2022, 1(3): 100059.

聯系方式：

郵箱：996996@hainanu.edu.cn